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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FIGN All Species: 10.61
Human Site: S162 Identified Species: 15.56
UniProt: Q5HY92 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q5HY92 NP_060556.2 759 82146 S162 A S N L T E P S Y S S S T C G
Chimpanzee Pan troglodytes XP_001153855 674 74011 N107 W Q S G L S I N N V F K M S S
Rhesus Macaque Macaca mulatta XP_001097992 759 82110 S162 A S N L T E P S Y S S S T C G
Dog Lupus familis XP_545496 695 74019 Q128 K N D S E P W Q P S L S A D A
Cat Felis silvestris
Mouse Mus musculus Q9ERZ6 759 82080 S162 A S N L T E P S Y S S S T C G
Rat Rattus norvegicus Q6GX84 677 74178 V110 S G L S I N N V F K M S T V Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506217 731 78137 S163 R S G L T M D S V F R S D R V
Chicken Gallus gallus Q5ZK92 613 66247 A46 P A G A A A A A A A S P H K R
Frog Xenopus laevis Q6DDU8 655 72133 I87 L N N Y A D S I L T M A K C Q
Zebra Danio Brachydanio rerio Q503S1 736 79183 G162 H A S A L H S G I P S Q E F A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VQN8 523 58530
Honey Bee Apis mellifera XP_625184 585 66969 L18 S E D M A A C L L Q R S L E D
Nematode Worm Caenorhab. elegans O16299 594 66169 D27 E T G E N N D D L Y P P T A L
Sea Urchin Strong. purpuratus XP_783737 603 65189 G36 M E D N A A S G G Q P P L K R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SEX2 523 57218
Baker's Yeast Sacchar. cerevisiae P39955 897 100313 K220 H N D P P L K K E T E L Y S D
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 37.6 99.4 72.9 N.A. 97.8 35.5 N.A. 31.6 24.8 35.7 71.2 N.A. 25.2 26.6 26.4 30.8
Protein Similarity: 100 54.9 99.4 79.1 N.A. 99.3 54.9 N.A. 47 42.2 53.4 83.7 N.A. 40.8 46.6 43.3 46.9
P-Site Identity: 100 0 100 13.3 N.A. 100 13.3 N.A. 33.3 6.6 13.3 6.6 N.A. 0 6.6 6.6 0
P-Site Similarity: 100 13.3 100 26.6 N.A. 100 26.6 N.A. 33.3 26.6 40 20 N.A. 0 26.6 13.3 6.6
Percent
Protein Identity: N.A. N.A. N.A. 23.9 25 N.A.
Protein Similarity: N.A. N.A. N.A. 39.2 40.5 N.A.
P-Site Identity: N.A. N.A. N.A. 0 0 N.A.
P-Site Similarity: N.A. N.A. N.A. 0 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 19 13 0 13 25 19 7 7 7 7 0 7 7 7 13 % A
% Cys: 0 0 0 0 0 0 7 0 0 0 0 0 0 25 0 % C
% Asp: 0 0 25 0 0 7 13 7 0 0 0 0 7 7 13 % D
% Glu: 7 13 0 7 7 19 0 0 7 0 7 0 7 7 0 % E
% Phe: 0 0 0 0 0 0 0 0 7 7 7 0 0 7 0 % F
% Gly: 0 7 19 7 0 0 0 13 7 0 0 0 0 0 19 % G
% His: 13 0 0 0 0 7 0 0 0 0 0 0 7 0 0 % H
% Ile: 0 0 0 0 7 0 7 7 7 0 0 0 0 0 0 % I
% Lys: 7 0 0 0 0 0 7 7 0 7 0 7 7 13 0 % K
% Leu: 7 0 7 25 13 7 0 7 19 0 7 7 13 0 7 % L
% Met: 7 0 0 7 0 7 0 0 0 0 13 0 7 0 0 % M
% Asn: 0 19 25 7 7 13 7 7 7 0 0 0 0 0 0 % N
% Pro: 7 0 0 7 7 7 19 0 7 7 13 19 0 0 0 % P
% Gln: 0 7 0 0 0 0 0 7 0 13 0 7 0 0 13 % Q
% Arg: 7 0 0 0 0 0 0 0 0 0 13 0 0 7 13 % R
% Ser: 13 25 13 13 0 7 19 25 0 25 32 44 0 13 7 % S
% Thr: 0 7 0 0 25 0 0 0 0 13 0 0 32 0 0 % T
% Val: 0 0 0 0 0 0 0 7 7 7 0 0 0 7 7 % V
% Trp: 7 0 0 0 0 0 7 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 7 0 0 0 0 19 7 0 0 7 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _